MDMB-4en-PINACA-d4 (CRM)

MDMB-4en-PINACA-d₄ (CRM) is intended for use as an internal standard for the quantification of MDMB-4en-PINACA in a drug discrimination test and induces hypothermia in mice.^[2] MDMB-4en-PINACA has been associated with overdose and found in samples seized by law enforcement.^3,4 MDMB-4en-PINACA-d₄ is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

References:
[1].Cannaert, A., Sparkes, E., Pike, E., et al.Synthesis and in vitro cannabinoid receptor 1 activity of recently detected synthetic cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL-CBMICA, ADB-BINACA, APP-BINACA, 4F-MDMB-BINACA, MDMB-4en-PINACA, A-CHMINACA, 5F-AB-P7AICA, 5F-MDMB-P7AICA, and 5F-AP7AICAACS Chem. Neurosci.11(24)4434-4446(2020).
[2].Marusich, J.A., Gamage, T.F., Zhang, Y., et al.In vitro and in vivo pharmacology of nine novel synthetic cannabinoid receptor agonistsPharmacol. Biochem. Behav.220173467(2022).
[3].Manini, A.F., Krotulski, A.J., Schimmel, J., et al.Respiratory failure in confirmed synthetic cannabinoid overdoseClin. Toxicol. (Phila)60(4)524-526(2022).
[4].Rodrigues, T.B., Souza, M.P., de Melo Barbosa, L., et al.Synthetic cannabinoid receptor agonists profile in infused papers seized in Brazilian prisonsForensic Toxicol.40(1)119-124(2022).