GlpBio

m-PEG8-Amine

目录号: GC62543纯度: >98.00%同义词: 3,6,9,12,15,18,21,24-八氧杂二十五烷-1-胺
m-PEG8-Amine 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联药物 (ADCs) 的合成。
m-PEG8-Amine
Cas No.: 869718-81-0
规格价格库存数量操作
50mg¥90.00现货
1
100mg¥135.00现货
1
500mg¥234.00现货
1
1g¥402.00现货
1
5g¥1,729.00现货
1
10g¥3,312.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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产品描述 Description

m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Joshua D. Thoma, et al. Pyrrolobenzodiazepine antibody conjugates. WO2019126691A1.

产品文档 Product Documents

Purity:>98.00%Appearance:A liquid

化学性质Chemical Properties

CAS 号
869718-81-0
同义词
3,6,9,12,15,18,21,24-八氧杂二十五烷-1-胺
分子式
C17H37NO8
分子量
383.48 g/mol
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol