Lipid 14 is an ionizable cationic amino lipid that has been used in the formation of lipid nanoparticles (LNPs).1 LNPs containing lipid 14 and encapsulating mRNA encoding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein receptor-binding domain (RBD), also known as the surface glycoprotein RBD, increase anti-RBD antibody levels in mice, as well as increase the number of isolated mouse splenocytes secreting IFN-γ and IL-2, but not IL-4 or IL-10, when incubated with the SARS-CoV-2 spike glycoprotein. LNPs containing lipid 14 and encapsulating mRNA encoding the bacterial Caf1 (F1) capsule antigen from Y. pestis, the bacteria that causes bubonic plague, induces anti-F1 cellular and humoral responses and protects against lethal Y. pestis infection in mice.2
Lipid 14
目录号: GC90932纯度: >95.00%
一种可离子化的阳离子氨基脂质
Cas No.: 2430034-05-0
| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 5mg | ¥2,340.00 | 现货 | 1 | |
| 10mg | ¥3,600.00 | 现货 | 1 | |
| 10mM (in 1mL DMSO) | ¥7,128.00 | 现货 | 1 |
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文献被引
本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
产品描述 Description
产品文档 Product Documents
Purity:>95.00%Appearance:A solution in methyl acetate
化学性质Chemical Properties
CAS 号
2430034-05-0
分子式
C56H110N2O6
分子量
907.5 g/mol
溶解性
Ethanol: Soluble,Methyl Acetate: 25 mg/mL
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。
计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度
g/mol