GlpBio

L-319

目录号: GC49721纯度: >95.00%同义词: Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
An ionizable cationic and biodegradable lipid
L-319
Cas No.: 1351586-50-9
规格价格库存数量操作
1mg¥585.00现货
1
5mg¥1,386.00现货
1
10mg¥2,067.00现货
1
25mg¥3,502.00现货
1
50mg¥5,173.00现货
1
10mM (in 1mL DMSO)¥2,067.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

L-319 is an ionizable (pKa = 6.38) and biodegradable lipid that has been used in the formation of lipid nanoparticles.1 Administration of mouse factor VII-targeting siRNA in L-319-containing lipid nanoparticles induces factor VII silencing in mice.

1.Maier, M.A., M., J., Matsuda, S., et al.Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeuticsMol. Ther.21(8)1570-1578(2013)

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
1351586-50-9
同义词
Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
SMILES
CN(C)CCCC(OC(CCCCCCCC(OC/C=C\CCCCCC)=O)CCCCCCCC(OC/C=C\CCCCCC)=O)=O
分子式
C41H75NO6
分子量
678 g/mol
溶解性
DMSO : 100 mg/mL (147.48 mM; Need ultrasonic)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol