GlpBio

Isatin-β-thiosemicarbazone

目录号: GC69291纯度: >99.00%同义词: IBT
Isatin-β-thiosemicarbazone 是一种有效的抗痘病毒剂 (anti-poxvirus；包括猴痘病毒、正痘病毒、牛痘病毒等)。Isatin-β-thiosemicarbazone 也是一种有效的单纯疱疹病毒 (HSV) 抑制剂。Isatin-β-thiosemicarbazone 在对 HSV-1 和 HSV-2 都具有抗病毒活性。
Isatin-β-thiosemicarbazone
Cas No.: 27830-79-1
规格价格库存数量操作
100mg¥4,500.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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产品描述 Description

Isatin-β-thiosemicarbazone is a potent anti-poxvirus agent (including monkeypox virus, HSV) inhibitor. Isatin-β-thiosemicarbazone exhibits

[1]. Meis RJ, et al. Genetic and molecular biological characterization of a vaccinia virus gene which renders the virus dependent on isatin-beta-thiosemicarbazone (IBT). Virology. 1991 Jun;182(2):442-54.
[2]. Katz E, et al. Synthesis of vaccinia virus polypeptides in the presence of isatin-beta-thiosemicarbazone. Antimicrob Agents Chemother. 1973 Jul;4(1):44-8.
[3]. Iou-Jiun Kang, et al. Isatin-β-thiosemicarbazones as potent herpes simplex virus inhibitors. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1948-52.
[4]. William D Arndt, et al. Monkeypox virus induces the synthesis of less dsRNA than vaccinia virus, and is more resistant to the anti-poxvirus drug, IBT, than vaccinia virus. Virology. 2016 Oct;497:125-135.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
27830-79-1
同义词
IBT
分子式
C9H8N4OS
分子量
220.25 g/mol
溶解性
DMSO : 125 mg/mL (567.54 mM; Need ultrasonic)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol