GlpBio

Indolicidin (trifluoroacetate salt)

目录号: GC52395纯度: >98.00%同义词: ILPWKWPWWPWRR-NH2
An antimicrobial peptide
Indolicidin (trifluoroacetate salt)
规格价格库存数量操作
1 mg¥3,262.00现货
1
5 mg¥12,418.00现货
1
10 mg¥22,918.00现货
1
500 μg¥1,918.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Indolicidin is an antimicrobial peptide.1 It is active against multidrug-resistant isolates of enteroaggregative E. coli (MDR-EAEC; MICs = 32 µM for all). Indolicidin is also active against S. cerevisiae, T. beigelii, and C. albicans (MICs = 5-10, 2.5-5, and 5-10 µM, respectively) and reduces viral replication of HIV-1 in MT-2 cells when used at concentrations ranging from 67 to 100 µg/ml.2,3 In vivo, indolicidin increases survival of MDR-EAEC-infected G. mellonella larvae.1

1.Vergis, J., Malik, S.S., Pathak, R., et al.Antimicrobial efficacy of indolicidin against multi-drug resistant enteroaggregative Escherichia coli in a Galleria mellonella modelFront. Microbiol.102723(2019) 2.Lee, D.G., Kim, H.K., Kim, S.A., et al.Fungicidal effect of indolicidin and its interaction with phospholipid membranesBiochem. Biophys. Res. Commun.305(2)305-310(2003) 3.Robinson, W.E., Jr., McDougall, B., Tran, D., et al.Anti-HIV-1 activity of indolicidin, an antimicrobial peptide from neutrophilsJ. Leukoc. Biol.63(1)94-100(1998)

产品文档 Product Documents

Purity:>98.00%Appearance:A solid

化学性质Chemical Properties

同义词
ILPWKWPWWPWRR-NH2
SMILES
NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@@H]3CCCN3C([C@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CC6=CNC7=C6C=CC=C7)NC([C@@H]8CCCN8C([C@H](CC9=CNC%10=C9C=CC=C%10)NC([C@H](CCCCN[H])NC([C@H](CC%11=CNC%12=C%11C=CC=C%12)NC([C@@H]%13CCCN%13C([C@@H](NC([C@](N[H])([H])[C@@H](C)CC)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
分子式
C100H132N26O13 ? XCF3COOH
分子量
1906.3 g/mol
溶解性
DMF: 10 mg/ml,DMSO: 5 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): insol
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol