GlpBio

IM21.7c

目录号: GC91587纯度: >95.00%
IM21.7c is a cationic lipid that has been used in the generation of lipid nanoparticles for the delivery of mRNA in vitro and in vivo.
IM21.7c
Cas No.: 2416939-42-7
规格价格库存数量操作
5 mg¥4,760.00现货
1
10 mg¥8,568.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

IM21.7c is a cationic lipid that has been used in the generation of lipid nanoparticles for the delivery of mRNA in vitro and in vivo.[1] Intravenous administration of LNPs containing IM21.7c and encapsulating an mRNA reporter selectively accumulate in the lungs and spleen over the liver in mice.

References:
[1].Guéguen, C., Ben Chimol, T., Briand, M., et al.Evaluating how cationic lipid affects mRNA-LNP physical properties and biodistributionEur. J. Pharm. Biopharm.195114077(2024).

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
2416939-42-7
分子式
C59H117N2•Cl
分子量
890 g/mol
溶解性
DMSO: Slightly soluble: 0.1-1 mg/ml,Ethanol: Sparingly soluble: 1-10 mg/ml,PBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol