GlpBio

IDR 1002 (trifluoroacetate salt)

目录号: GC52346纯度: >95.00%
A synthetic cationic innate defense regulator peptide
IDR 1002 (trifluoroacetate salt)
规格价格库存数量操作
5 mg¥1,064.00现货
1
10 mg¥1,918.00现货
1
25 mg¥4,522.00现货
1
50 mg¥8,512.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

IDR 1002 is a synthetic cationic innate defense regulator peptide.1 It increases the production of chemokine (C-C motif) ligand 2 (CCL2), CCL7, and chemokine (C-X-C motif) ligand 1 (CXCL1) in isolated human peripheral blood mononuclear cells (PBMCs) when used at a concentration of 100 µg/ml. IDR 1002 (200 µg/animal) increases the numbers of neutrophils and monocytes in mouse peritoneum and protects against S. aureus and E. coli infections in mice.

1.Nijnik, A., Madera, L., Ma, S., et al.Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitmentJ. immunol.184(5)2539-2550(2010)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

SMILES
NCCCC[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](C(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@@H](N)C(C)C)=O)=O)=O)CC1=CNC2=CC=CC=C12)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O.OC(C(C)(F)F)=O
分子式
C79H130N26O13 ? XCF3COOH
分子量
1652 g/mol
溶解性
DMSO: Slightly soluble,PBS (pH 7.2): Slightly soluble
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol