IB-96212 is a macrolide that has been found in Micromonospora and has antibacterial and anticancer activities.[1] It is active against M. luteus, B. subtilis, and S. aureus (MICs = 0.4, 100, and 100 µg/ml, respectively). IB-96212 induces death in P388 leukemia, A549 lung cancer, HT-29 colon cancer, and SK-MEL-28 melanoma cells (IC50s = 0.0001, 1, 1, and 1 µg/ml, respectively).
References:
[1].Fernández-Chimeno, R.I., Cañedo, L., Espliego, F., et al.IB-96212, a novel cytotoxic macrolide produced by a marine Micromonospora. I. Taxonomy, fermentation, isolation and biological activitiesJ. Antibiot. (Tokyo)53(5)474-478(2000).
















