GlpBio

Histone H4R3Me2s (1-21)-GGK-biotin (trifluoroacetate salt)

目录号: GC90333纯度: >95.00%同义词: Ac-SG-R(me2s)-GKGGKGLGKGGAKRHRKV-GGK(Biotin), Arg(Me2s)3-Histone H4 (1-21)-GGK(Biotin), Histone H4 (1-21) (Arg3me2s)

一段带有生物素的组蛋白H4肽片段。

Histone H4R3Me2s (1-21)-GGK-biotin (trifluoroacetate salt)
规格价格库存数量操作
250 μg¥3,879.00现货
1
电话: 400-920-5774Email: sales@glpbio.cn

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Histone H4R3Me2s (1-21)-GGK-biotin is a peptide fragment of histone H4 that corresponds to amino acid residues 2-22 of the human H4 sequence. It is symmetrically dimetlated at arginine 3 and biotinylated via a C-terminal GGK linker. Symmetric dimetlation of histone 4 at arginine 3 is associated with transcriptional repression.1 It can recruit the DNA metltransferase DNMT3a, leading to DNA metlation and further transcriptional repression. Histone H4R3Me2s (1-21)-GGK-biotin has been used as a substrate for the qualitative measurement of jumonji domain containing 1B (JMJD1B) arginine demetlase activity and in dot blot assays to verify antibody specificity.2

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

同义词
Ac-SG-R(me2s)-GKGGKGLGKGGAKRHRKV-GGK(Biotin), Arg(Me2s)3-Histone H4 (1-21)-GGK(Biotin), Histone H4 (1-21) (Arg3me2s)
分子式
C111H197N43O29S • XCF3COOH
分子量
2630.1 g/mol
溶解性
Water: 1 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol