GlpBio

Histatin 5 (trifluoroacetate salt)

目录号: GC52416纯度: >98.00%同义词: DSHAKRHHGYKRKFHEKHHSHRGY, Hst-5
An antimicrobial peptide
Histatin 5 (trifluoroacetate salt)
规格价格库存数量操作
1 mg¥392.00现货
1
5 mg¥1,750.00现货
1
10 mg¥3,080.00现货
1
25 mg¥6,748.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Histatin 5 is a salivary antimicrobial peptide.1,2,3 It is active against C. albicans (LC50 = 1.8 µM), as well as A. baumannii, P. aeruginosa, and E. cloacae (MICs = 38, 47, and 90 µM, respectively).1,2 Topical application of histatin 5 (20 µM) decreases fungal burden in a mouse model of C. albicans-induced vulvovaginal candidiasis.3

1.Edgerton, M., Koshlukova, S.E., Lo, T.E., et al.Candidacidal activity of salivary histatinsJ. Biol. Chem.273(32)20438-20447(1998) 2.Du, H., Puri, S., McCall, A., et al.Human salivary protein histatin 5 has potent bactericidal activity against ESKAPE pathogensFront. Cell. Infect. Microbiol.741(2017) 3.Liao, H., Liu, S., Wang, H., et al.Efficacy of Histatin5 in a murine model of vulvovaginal candidiasis caused by Candida albicansPathog. Dis.75(6)(2017)

产品文档 Product Documents

Purity:>98.00%Appearance:A solid

化学性质Chemical Properties

同义词
DSHAKRHHGYKRKFHEKHHSHRGY, Hst-5
SMILES
OC(C=C1)=CC=C1C[C@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](C)NC([C@@H](NC([C@H](CO)NC([C@@H](N)CC(O)=O)=O)=O)CC2=CN=CN2)=O)=O)=O)=O)CC3=CN=CN3)=O)CC4=CN=CN4)=O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC5=CC=CC=C5)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@H](C(O)=O)CC6=CC=C(C=C6)O)=O)=O)=O)CC7=CN=CN7)=O)=O)CC8=CN=CN8)=O)CC9=CN=CN9)=O)=O)=O)CC%10=CN=CN%10)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
分子式
C133H195N51O33 ? XCF3COOH
分子量
3036.3 g/mol
溶解性
DMF: 12 mg/ml,DMSO: 10 mg/ml,Ethanol: 12 mg/ml,PBS (pH 7.2): 5 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol