Heptacosanoic Acid is a kind of very long chain fatty acids which is an important component of lipid in most organisms [1]. The proportion of Heptacosanoic Acid in the erythrocyte of adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN) patients was higher and the aggregation of Heptacosanoic Acid increased the index of microviscosity of erythrocyte membranes [2].
References:
[1] Kyselová L, Vítová M, Řezanka T. Very long chain fatty acids [J]. Progress in lipid research, 2022, 87: 101180.
[2] Knazek R A, Rizzo W B, Schulman J D, et al. Membrane microviscosity is increased in the erythrocytes of patients with adrenoleukodystrophy and adrenomyeloneuropathy [J]. The Journal of clinical investigation, 1983, 72(1): 245-248.
Heptacosanoic Acid是一种超长链脂肪酸，是大多数生物体中脂质的重要组成部分[1]。在肾上腺脑白质营养不良（ALD）和肾上腺脊髓神经病（AMN）患者的红细胞中，Heptacosanoic Acid的占比更高，且Heptacosanoic Acid的聚集会使红细胞膜的微粘度指数升高[2]。