GlpBio

GSK5182

目录号: GC64453纯度: >98%
COASDSData Sheet
GSK5182, 4-hydroxytamoxifen analog, is a specific inverse agonist of estrogen-related receptor γ (ERRγ) that inhibits pro-inflammatory cytokine-induced catabolic factors.
GSK5182
Cas No.: 877387-37-6
规格价格库存数量操作
5 mg¥1,170.00现货
1
10 mg¥1,710.00现货
1
25 mg¥3,150.00现货
1
50 mg¥4,770.00现货
1
100 mg¥7,200.00现货
1
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文献被引

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产品描述 Description

GSK5182, 4-hydroxytamoxifen analog, is a specific inverse agonist of estrogen-related receptor γ (ERRγ) that inhibits pro-inflammatory cytokine-induced catabolic factors.

GSK5182, a small-molecule ERRγ inverse agonist, inhibits pro-inflammatory cytokine-induced catabolic factors in mouse articular chondrocytes.[1]

GSK5182 significantly reduces cartilage degeneration in ERRγ-overexpressing mice administered intra-articular Ad-Esrrg.[1]

[1] Yunhui Min, et al. Pharmaceuticals (Basel). 2020 Nov 27;13(12):429.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
877387-37-6
分子式
C27H31NO3
分子量
417.54 g/mol
溶解性
DMSO : 25 mg/mL (59.87 mM; ultrasonic and warming and heat to 80°C)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol