GlpBio

GRGDSPK (EMD 56574)

目录号: GC30585纯度: >98.00%同义词: EMD 56574
GRGDSPK (EMD 56574) (EMD 56574) 是一种包含 Arg-Gly-Asp (RGD) 的肽。
GRGDSPK (EMD 56574)
Cas No.: 111119-28-9
规格价格库存数量操作
1mg¥450.00现货
1
5mg¥990.00现货
1
10mg¥1,485.00现货
1
25mg¥2,520.00现货
1
50mg¥3,780.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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产品描述 Description

GRGDSPK is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.

GRGDSPK inhibits the adhesion of Rat PDL cells[1]. RGD-containing (GRGDSPK, 1.5 mM, 1.0 mM, and 0.5 mM) and RGD-mod-ified peptides impair the ability of sperm to fertilizebovine oocytes, illustrated by a reduction in cleavage in a dose-dependent manner[2].

[1]. Hatakeyama J, et al. Proliferation and adhesion of periodontal ligament cells on synthetic biominerals. Oral Dis. 2007 Sep;13(5):500-6. [2]. Sessions BR, et al. Effects of amino acid substitutions in and around the arginine-glycine-aspartic acid (RGD) sequence on fertilization and parthenogenetic development in mature bovine oocytes. Mol Reprod Dev. 2006 May;73(5):651-7.

实验参考方法 Experimental Reference Method

Cell experiment:

Proliferation assays are carried out in 48-well cell culture dishes coated with OCP or HL. In proliferation assays, 7.25×103 cells in 0.5 mL of culture medium are seeded in a 48-well dish. Culture medium is changed every 3 days. After 1, 6, 12, and 18 days of culture, plates are washed thrice with PBS to remove unattached cells, and attached cells are collected by trypsinization. The number of cells is counted using a hemocytometer.

References:

[1]. Hatakeyama J, et al. Proliferation and adhesion of periodontal ligament cells on synthetic biominerals. Oral Dis. 2007 Sep;13(5):500-6.
[2]. Sessions BR, et al. Effects of amino acid substitutions in and around the arginine-glycine-aspartic acid (RGD) sequence on fertilization and parthenogenetic development in mature bovine oocytes. Mol Reprod Dev. 2006 May;73(5):651-7.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
111119-28-9
同义词
EMD 56574
SMILES
Gly-Arg-Gly-Asp-Ser-Pro-Lys
分子式
C28H49N11O11
分子量
715.76 g/mol
溶解性
Soluble in Water
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol