GFOGER peptide is a α2β1, α1β1 and α11β1 integrin ligand peptide. GFOGER peptide can be recognized via directly interactions of integrins with its Glu and Arg residues, particularly binding to Glu through the metal ion-dependent adhesion site (MIDAS)[1].
References:
[1]. Zhang WM, et al. alpha 11beta 1 integrin recognizes the GFOGER sequence in interstitial collagens. J Biol Chem. 2003 Feb 28;278(9):7270-7.
GFOGER peptide 是一种 α2β1、α1β1 和 α11β1 整合素配体肽。GFOGER peptide 可以通过整合素与其 Glu 和 Arg 残基的直接相互作用而被识别，特别是通过金属离子依赖性粘附位点 (MIDAS) 与 Glu 的结合。