Saikosaponin F is a triterpenoid saponin that has been found in B. chinensis and an antagonist of transient receptor potential ankyrin 1 (TRPA1).1 It inhibits calcium flux induced by polygodial or AITC in HEK293 cells expressing human TRPA1 when used at concentrations ranging from 0.5 to 1.5 ?M.
1.Lee, G., Choi, J., Nam, Y.-J., et al.Identification and characterization of saikosaponins as antagonists of transient receptor potential A1 channelPhytother Res.34(4)788-795(2020)
















