Rocuronium is a non-depolarizing muscle relaxant.1 It selectively induces neuromuscular blockade in cats (ED50s = 153, 185, 1,329, and 4,119 μg/kg for tibialis, soleus, and vagus muscles, and nictitating membranes, respectively) with a more rapid onset time than vecuronium . Formulations containing rocuronium have been used for surgical anesthesia.2
1.Muir, A.W., Houston, J., Green, K.L., et al.Effects of a new neuromuscular blocking agent (Org 9426) in anaesthetized cats and pigs and in isolated nerve-muscle preparationsBr. J. Anaesth.63(4)400-410(1989) 2.Fawcett, W.J., Fauvel, N.J., and Feldman, S.A.Comparison of recovery index of rocuronium or vecuronium with simultaneously administered pancuronium in the isolated forearmAnaesthesia48(3)200-201(1993)