Iopamidol (Iopamiro, Isovue, Iopamiron, Niopam, Solutrast,B-15000,SQ-13396) is a non-ionic, water-soluble radiographic contrast agent.
Iopamidol significantly decreases the rate of atrial contraction to a greater extent than either formulation of iodixanol. Iopamidol decreases papillary muscle force development more than the sodium formulation of iodixanol[3].
Iopamidol increases systolic blood pressure (SBP), mean arterial pressure (MAP), and peak left ventricular pressure (LVP). Iopamidol increases LVP and LV end diastolic pressure to a greater extent than the cationic formulation of iodixanol. Thus iopamidol affects cardiovascular parameters more than iodixanol[3].
[1] Longo DL, et al. Magn Reson Med. 2011, 65(1):202-11. [2] Doan R, et al. 55th Annual Meeting of the Orthopaedic Research Society. Poster No.2166 [3] Dundore RL, et al. Invest Radiol. 1991, 26(8):715-21.