Quercetin 3-O-α-L-arabinopyranoside is a phenol that has been found in Byrsonima crassa and has antioxidant activity.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 48.6 ?M).1 Quercetin 3-O-α-L-arabinopyranoside inhibits H. pylori-induced oxidative burst of isolated rat polymorphonuclear (PMN) neutrophils (IC50 = 75.3 ?M).2 It reduces N-retinylidene-N-retinylethanolamine- and blue light-induced death of ARPE-19 retinal epithelial cells in a concentration-dependent manner.3 In vivo, quercetin 3-O-α-L-arabinopyranoside (25, 50, and 200 mg/kg) prevents blue light-induced retinal degeneration in a mouse model of macular degeneration.
1.Joshi, K.R., Devkota, H.P., Watanabe, T., et al.Phenolic compounds from the flowers of Nepalese medicinal plant Aconogonon molle and their DPPH free radical-scavenging activitiesNat. Prod. Res.28(23)2208-2210(2014) 2.Bonacorsi, C., Raddi, M.S.G., da Fonseca, L.M., et al.Effect of Byrsonima crassa and phenolic constituents on Helicobacter pylori-induced neutrophils oxidative burstInt. J. Mol. Sci.13(1)133-141(2012) 3.Kim, J., Jin, H.L., Jang, D.S., et al.Quercetin-3-O-α-l-arabinopyranoside protects against retinal cell death via blue light-induced damage in human RPE cells and Balb-c miceFood Funct.9(4)2171-2183(2018)