Araloside A is a triterpenoid saponin that has been found in A. taibaiensis and has anti-inflammatory and gastroprotective effects.1,2 It increases apoptosis of and decreases production of IL-1β and IL-6 in human MH7A rheumatoid arthritis fibroblast-like synoviocytes when used at concentrations ranging from 4 to 16 ?M.1 Araloside A (50 and 100 mg/kg) reduces gastric acid secretion and lesion size in rat models of hydrochloric acid and ethanol-, aspirin-, water immersion stress-, or pyloric ligation-induced ulcer formation.2
1.Ding, Y., Zhao, Q., and Wang, L.Pro-apoptotic and anti-Inflammatory effects of araloside A on human rheumatoid arthritis fibroblast-like synoviocytesChem. Biol. Interact.306131-137(2019) 2.Lee, E.B., Kim, O.J., Kang, S.S., et al.Araloside A, an antiulcer constituent from the root bark of Aralia elataBiol. Pharm. Bull.28(3)523-526(2005)