GlpBio

12-Epinapelline

目录号: GC35054纯度: >98.00%同义词: 12-表-欧乌头碱
A diterpenoid alkaloid with antiarrhythmic activity
12-Epinapelline
Cas No.: 110064-71-6
规格价格库存数量操作
1mg¥450.00现货
1
5mg¥792.00现货
1
10mg¥1,195.00现货
1
25mg¥1,827.00现货
1
50mg¥2,709.00现货
1
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文献被引

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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

12-Epinapelline is a diterpenoid alkaloid that has been found in Aconitum and has antiarrhythmic activity.1 It has antiarrhythmic activity in a rat model of aconitine-induced arrhythmia and antifibrillatory activity in a mouse model of aconitine-induced cardiac fibrillation (ED50s = 8 and 20 mg/kg, respectively).

1.Dzhakhangirov, F.N., Sultankhodzhaev, M.N., Tashkhodzhaev, B., et al.Diterpenoid alkaloids as a new class of antiarrhythmic agents. Structure-activity relationshipChem. Nat. Compd.33(2)190-202(1997)

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
110064-71-6
同义词
12-表-欧乌头碱
SMILES
O[C@@H](CC[C@]1(C)[C@@]2([H])C3)C42[C@@](C[C@@H](O)[C@]5([H])C6)([H])[C@@]6([C@@H](C5=C)O)C3C4N(C1)CC
分子式
C22H33NO3
分子量
359.5 g/mol
溶解性
DMSO : 100 mg/mL (278.16 mM; Need ultrasonic)
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol