GlpBio

GAPDH Inhibitor Compound F8

目录号: GC91975纯度: >95.00%
GAPDH Inhibitor Compound F8是GAPDH共价抑制剂（IC50 = 39.31 μM）。
GAPDH Inhibitor Compound F8
Cas No.: 252212-58-1
规格价格库存数量操作
1 mg¥490.00现货
1
5 mg¥2,212.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

GAPDH inhibitor compound F8 is a covalent inhibitor of GAPDH (IC50 = 39.31 μM).1 It viability of, and glucose metabolism in, HEK293 cells in a concentration-dependent manner.

References:
[1]. Jung, Y., Noda, N., Takaya, J., et al.Discovery of non-cysteine-targeting covalent inhibitors by activity-based proteomic screening with a cysteine-reactive probeACS Chem. Biol.17(2)340-347(2022).

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
252212-58-1
化学名
2,5-bis[3-(2-oxiranylmethoxy)phenyl]-1,3,4-oxadiazole
SMILES
C1(C2=CC(OCC3OC3)=CC=C2)=NN=C(C4=CC=CC(OCC5CO5)=C4)O1
分子式
C20H18N2O5
分子量
366.4 g/mol
溶解性
Acetonitrile: Slightly soluble: 0.1-1 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol