Z-Lys-SBzl . HCl is a lysine derivative and a protease assay substrate. Z-Lys-SBzl . HCl serves as a thioester substrate for photometric assays to detect enzyme activity. Z-Lys-SBzl . HCl can be used in research related to protease activity determination and as an intermediate in peptide synthesis[1-4].
References:
[1] Gasparian ME, Ostapchenko VG, Schulga AA, et al. Expression, purification, and characterization of human enteropeptidase catalytic subunit in Escherichia coli. Protein Expr Purif. 2003 Sep;31(1):133-9.
[2] Gasparian ME, Ostapchenko VG, Dolgikh DA, et al. Biochemical characterization of human enteropeptidase light chain. Biochemistry (Mosc). 2006 Feb;71(2):113-9.
[3] Lawson JH, Mann KG. Cooperative activation of human factor IX by the human extrinsic pathway of blood coagulation. J Biol Chem. 1991 Jun 15;266(17):11317-27.
[4] Wilharm E, Tschopp J, Jenne DE. Biological activities of granzyme K are conserved in the mouse and account for residual Z-Lys-SBzl activity in granzyme A-deficient mice. FEBS Lett. 1999 Oct 1;459(1):139-42.
Z-Lys-SBzl . HCl是一种赖氨酸衍生物和蛋白酶测定底物。Z-Lys-SBzl . HCl可作为硫酯底物用于光度测定来检测酶活性。Z-Lys-SBzl . HCl可用于蛋白酶活性测定和多肽合成中间体的相关研究[1-4]。