PYR-GLN-OH is a bioactive pyroglutamyl dipeptide. As an additive to cell culture medium, PYR-GLN-OH can enhance cell growth and proliferation rates. PYR-GLN-OH can also be used as a protein stabilizer, playing a crucial role in protein expression and purification processes[1-2].
References:
[1] Bottesini C, Tedeschi T, Dossena A, et al. Enzymatic production and degradation of cheese-derived non-proteolytic aminoacyl derivatives. Amino Acids. 2014 Feb;46(2):441-7
[2] Kiyono T, Hirooka K, Yamamoto Y, et al. Identification of pyroglutamyl peptides in Japanese rice wine (sake): presence of hepatoprotective pyroGlu-Leu. J Agric Food Chem. 2013 Nov 27;61(47):11660-7
PYR-GLN-OH是一种具有生物活性的焦谷氨酰二肽。PYR-GLN-OH作为细胞培养基的添加剂，可以提高细胞的生长和增殖速率。PYR-GLN-OH还可以用作蛋白质的稳定剂，在蛋白质表达和纯化过程中发挥重要作用[1-2]。