DABCYL-γ-Abu-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Glu(EDANS)-Ala-Lys-NH₂

A selective fluorogenic (FRET) matrix metalloproteinase (MMP) substrate. The kcat/Km value for MMP-3 (Stromelysin-1) is 29.000 M⁻¹s⁻¹, for MMP-13 13.000 M⁻¹s⁻¹, and for MMP-9 7.500 M⁻¹s⁻¹ (at pH 7.5, 25 °C). The fluorescence increase is monitored using an excitation wavelength of 360 nm and an emission wavelength of 490 nm. No activity against this substrate could be measured with MMP1, MMP-7, and MMP-8 (kcat/Km < 1000 M⁻¹s⁻¹).