Ac-DL-Lys(Ac)-OH is a diacetyl derivative of lysine and can be used as a building block to synthesize inositol conjugates, which are applied in cancer-targeted therapy [1]. Ac-DL-Lys(Ac)-OH can form a complex with D-alanine-D-alanine and is used as a model molecule to develop surface stress sensors for detecting active free drugs[2].
References:
[1] Jaiswal M, Zhu S, Jiang W, et al. Synthesis and evaluation of N α, N ε-diacetyl-l-lysine-inositol conjugates as cancer-selective probes for metabolic engineering of GPIs and GPI-anchored proteins[J]. Organic & biomolecular chemistry, 2020, 18(15): 2938-2948.
[2] Ndieyira J W, Kappeler N, Logan S, et al. Surface-stress sensors for rapid and ultrasensitive detection of active free drugs in human serum[J]. Nature nanotechnology, 2014, 9(3): 225-232.
Ac-DL-Lys(Ac)-OH是赖氨酸的二乙酰化衍生物，可作为结构单元用于合成肌醇偶联物，应用于癌症靶向治疗[1]。Ac-DL-Lys(Ac)-OH可与D-丙氨酸-D-丙氨酸形成复合物，并用作模型分子来开发用于检测活性游离药物的表面应力传感器[2]。