GlpBio

FPI-1523 sodium

目录号: GC70836纯度: >99.00%
FPI-1523 sodium是Avibactam的衍生物，是一种有效的β-内酰胺酶抑制剂，对CTX-M-15和OXA-48的Kds分别为4 nM和34 nM。
FPI-1523 sodium
Cas No.: 1452459-52-7
规格价格库存数量操作
1mg¥757.00现货
1
5mg¥1,800.00现货
1
10mg¥2,880.00现货
1
25mg¥4,894.00现货
1
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产品描述 Description

FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity.

FPI-1523 sodium inhibits K12 E. coli K12 and PBP2, with MIC and IC50 of 4 μg/mL and 0.4 μg/mL, respectively[1].
FPI-1523 sodium inhibit E. coli BW25113 pGDP-2 transformants either with an empty vector or expressing different β-lactamases, with low MICs (1-2 μM)[1].

References:
[1]. King AM, et, al. Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. ACS Chem Biol. 2016 Apr 15;11(4):864-8.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
1452459-52-7
分子式
C9H13N4NaO7S
分子量
344.28 g/mol
溶解性
H<sub>2</sub>O : 125 mg/mL (363.08 mM; Need ultrasonic)
保存条件
4°C, sealed storage, away from moisture
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol