Fluorofurimazine is fluorogenic substrate for Antares. Fluorofurimazine can realize sensitive bioluminescence imaging to prolong the generation of high-sensitivity light. Fluorofurimazine has good aqueous solubility allows delivery of higher doses to mice. Fluorofurimazine can be used in the bioluminescence imaging[1].
Fluorofurimazine (562 μg; i.p.; for 30 days; nude mice) increases in peak signal when administered at 562 μg in vivo[1].
| Animal Model: | Nude mice[1] |
| Dosage: | 562 μg |
| Administration: | Intraperitoneal injection;for 30 days |
| Result: | Exhibited threefold bioluminescence than AkaLuc with AkaLumine. |
[1]. Su Y, et, al. Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals. Nat Methods. 2020 Aug;17(8):852-860.