FG-3019

目录号: GC69105纯度: >95.00%同义词: Pamrevlumab; Anti-Human CTGF Recombinant Antibody
FG-3019 (Pamrevlumab) 是一种重组人源化抗体,可与结缔组织生长因子 (CTGF) 结合。FG-3019 可用于特发性肺纤维化 (IPF) 的研究。

FG-3019
Cas No.: 946415-13-0
规格价格库存数量操作
5mg¥4,500.00现货
1
10mg¥7,200.00现货
1

文献被引

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    31, 1291–1307 (2021)

产品描述 Description

FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2].

FG-3019 (30 mg/kg; i.p. every 3 d for 9 d) 与 Gemcitabine 联合使用可显着降低小鼠胰腺导管腺癌 (PDA) 的生长,并诱导 LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) 小鼠中的肿瘤细胞凋亡[2]

[1]. Sgalla G, et, al. Pamrevlumab for the treatment of idiopathic pulmonary fibrosis. Expert Opin Investig Drugs. 2020 Aug;29(8):771-777.
[2]. Neesse A, et, al. CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12325-30.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
946415-13-0
同义词
Pamrevlumab; Anti-Human CTGF Recombinant Antibody
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算

g/mol