F4-Trp (4,5,6,7-Tetrafluoro-L-tryptophan) is a ligand targeting the α3β4 nicotinic acetylcholine receptor (α3β4nAChR). F4-Trp is promising for research of neurotransmission, addiction, and related diseases, such as neurological diseases[1].
References:
[1].Knox HJ, et al. Characterization of Binding Site Interactions and Selectivity Principles in the α3β4 Nicotinic Acetylcholine Receptor. J Am Chem Soc. 2022 Sep 7;144(35):16101-16117.
F4-Trp (4,5,6,7-Tetrafluoro-L-tryptophan) 是一种靶向 α3β4 型烟碱型乙酰胆碱受体 (α3β4nAChR) 的配体。F4-Trp 有望用于神经传递、成瘾及相关疾病的研究，如神经疾病。