Ethoprop-d6

Ethoprop-d₆ is intended for use as an internal standard for the quantification of ethoprop by GC- or LC-MS. Ethoprop is an organothiophosphate nematicide and insecticide.^1,2,3 It decreases the infectivity of M. chitwoodi and M. hapla second-stage juveniles (EC₅₀s = 5.6 and 6.8 μg/ml, respectively) and inhibits hatching of M. chitwoodi egg masses and M. chitwoodi and M. hapla free eggs (EC₅₀s = 0.2, 46, and 83.3 μg/ml, respectively).² Ethoprop (1.8 μg/g) decreases the number of M. chitwoodi nematodes in tomato roots when added to soil from fields without previous ethoprop exposure, but is biodegraded in soil from fields previously exposed to ethoprop. In field trials, it decreases the percentage of potato tubers damaged by wireworms when applied as granules in the planting furrow at a concentration of 3 kg AI/ha.³ Ethoprop is toxic to rats via oral administration and dermal contact (LD₅₀s = 47 and 226 mg/kg, respectively) as well as inhalation (LD₅₀ = 0.123 mg/L).¹ It is also toxic to bluegill (LC₅₀ = 0.32 mg/L). Formulations containing ethoprop have been used in the agricultural control of pests.