Ethopabate is a coccidiostat.1,2 In vivo, ethopabate reduces lesion score in broiler chickens infected with E. tenella, E. acervulina, and E. maxima field isolates when administered in combination with the antiprotozoal agent amprolium . Ethopabate has been found as a contaminant in environmental waters.3 Formulations containing ethopabate have been used to prevent coccidiosis in broiler chickens.
1.Mathis, G.F., and McDougald, L.R.Drug responsiveness of field isolates of chicken CoccidiaPoult. Sci.61(1)38-45(1982) 2.Oe, O., and Arakawa, A.Effect of feed additive antibiotics on chickens infected with Eimeria tenellaPoult. Sci.54(4)1008-1018(1975) 3.Mooney, D., Coxon, C., Richards, K.G., et al.A new sensitive method for the simultaneous chromatographic separation and tandem mass spectrometry detection of anticoccidials, including highly polar compounds, in environmental watersJ. Chromatogr. A1618460857(2020)