Egg oil (0.1-0.8 mg/ml) reduces IL-8 secretion and exerts anti-inflammatory efficacy through Nrf2/NF-kB signaling pathway[2].
Egg oil (10-600 μg/ml) extracted from sea urchin attenuates 7β-OHC induced cytotoxicity, modulates activity of antioxidant enzyme and reduces production of MDA and CD, exhibits thus protective efficacy against neurodegenerative diseases[4].
Egg oil (150-600 mg/kg, i.g. for 16 weeks) extracted from Portunus trituberculatus improves insulin sensibility and hepatic glycogen synthesis, alleviates insulin resistance through activation of PI3K/Akt/Glu4 signaling in skeletal muscle and PI3K/Akt/GSK3β/GS pathway in the liver[1].
Egg oil (150-600 mg/kg, i.g. for 16 weeks) extracted from Portunus trituberculatus amliorates HFD-induced obesity in mice, restores the gut microbial dysbiosis and down-regulates the LPS/TLR4 pathway in liver and epididymal adipose[3].
References:
[1]. Hu S, et al., Egg oil fromPortunus trituberculatus alleviates insulin resistance through activation of insulin signaling in mice. Appl Physiol Nutr Metab. 2019 Oct;44(10):1081-1088.
[2]. Xiao N, et al., Egg yolk oils exert anti-inflammatory effect via regulating Nrf2/NF-κB pathway. J Ethnopharmacol. 2021 Jun 28;274:114070.
[3]. Hu S, et al., Egg oil from Portunus trituberculatus alleviated obesity and regulated gut microbiota in mice. Sci Rep. 2020 May 21;10(1):8454.
[4]. Zarrouk A, et al., 7β-hydroxycholesterol-induced cell death, oxidative stress, and fatty acid metabolism dysfunctions attenuated with sea urchin egg oil. Biochimie. 2018 Oct;153:210-219.