EG1 is a specific Paired box 2 (Pax2) inhibitor that targets the DNA binding domain and inhibits embryonic kidney development.
EG1, a specific and efficacious Pax2 inhibitor that phenocopies a genetic loss of function, is capable of inhibiting Pax2 mediated expression of EGFP without significant effects on Pax2 protein levels.[1]
[1] Edward Grimley, et al. ACS Chem Biol. 2017 Mar 17;12(3):724-734.
















