GlpBio

DSPE-Polysarcosine66

目录号: GC92070纯度: >95.00%同义词: 1,2-Dioctadecanoyl-rac-glycero-3-Phosphoethanolamine-Polysarcosine66; 1,2-Distearoyl-rac-glycero-3-PE Polysarcosine66; 1,2-Distearoyl-rac-glycero-3-Phosphatidylethanolamine-Polysarcosine66; 1,2-Distearoyl-rac-glycero-3-Phosphoethanolamine-Polysarcosine66
DSPE-Polysarcosine66是一种胺官能化的亲水性聚合物。
DSPE-Polysarcosine66
规格价格库存数量操作
5 mg¥770.00现货
1
10 mg¥1,386.00现货
1
25 mg¥3,080.00现货
1
50 mg¥5,390.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

DSPE-polysarcosine66 is an amine-functionalized hydrophilic polymer. It is a polysarcosine-labeled form of 1,2-distearoyl-rac-glycero-3-phosphoethanolamine (DSPE). Polysarcosines have been used as alternatives to PEGylation in lipid nanoparticles (LNPs) and to reduce the immunogenicity of administered proteins in vivo.1,2

References:
[1]. Nogueira, S.S., Schlegel, A., Maxeiner, K., et al.Polysarcosine-functionalized lipid nanoparticles for therapeutic mRNA deliveryACS Appl. Nano Mater.3(11)10634-10645(2020).
[2]. Hu, Y., Hou, Y., Wang, H., et al.Polysarcosine as an alternative to PEG for therapeutic protein conjugationBioconjug. Chem.29(7)2232-2238(2018).

产品文档 Product Documents

Purity:>95.00%Appearance:A solution in methanol

化学性质Chemical Properties

同义词
1,2-Dioctadecanoyl-rac-glycero-3-Phosphoethanolamine-Polysarcosine66; 1,2-Distearoyl-rac-glycero-3-PE Polysarcosine66; 1,2-Distearoyl-rac-glycero-3-Phosphatidylethanolamine-Polysarcosine66; 1,2-Distearoyl-rac-glycero-3-Phosphoethanolamine-Polysarcosine66
化学名
(2R)-3-((hydroxy(2-(2-(methyl((methylamino)methyl)amino)acetamido)ethoxy)phosphoryl)oxy)propane-1,2-diyl distearate
SMILES
CCCCCCCCCCCCCCCCCC(OC[C@@](COP(O)(OCCNC(CN(C)CNC)=O)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)=O
分子式
(C3H5NO)nC43H87N2O8P
分子量
862.2 g/mol
溶解性
Chloroform: Soluble
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol