DOTA-NHS-ester TFA is used as a linker for affibody molecules, and it can be employed in small animal positron emission tomograp (PET), single photon emission computed tomograp (SPECT), and CT scanning. DOTA-NHS-ester can be used to label radiotracers or imaging probes for tumor detection.
References:
[1]. Hoppmann S, et al. Radiolabeled affibody-albumin bioconjugates for HER2-positive cancer targeting. Bioconjug Chem. 2011 Mar 16;22(3):413-21.
















