GlpBio

DOPE-PEG-COOH (MW 2000)

目录号: GC74697纯度: >95.00%
DOPE-PEG-COOH (MW 2000)是一个基于peg的PROTAC链接器。
DOPE-PEG-COOH (MW 2000)
规格价格库存数量操作
25 mg¥1,350.00现货
1
50 mg¥2,160.00现货
1
100 mg¥3,510.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

DOPE-PEG-COOH (MW 2000) is a PEG-based PROTAC linker. DOPE-PEG-COOH (MW 2000) can be used in the synthesis of PROTACs. DOPE-PEG-COOH (MW 2000) can be used for drug delivery, gene transfection and vaccine delivery.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References:
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

产品文档 Product Documents

Purity:>95.00%Appearance:An oil

化学性质Chemical Properties

分子量
2000(Average) g/mol
溶解性
DMSO : 100 mg/mL (Need ultrasonic)
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol