Desvaleryl valsartan is a potential impurity found in commercial preparations of the angiotensin II type 1 (AT1) receptor antagonist valsartan.1 It is a degradation product formed under acidic conditions.2
1.Krishnaiah, C., Reddy, A.R., Kumar, R., et al.Stability-indicating UPLC method for determination of valsartan and their degradation products in active pharmaceutical ingredient and pharmaceutical dosage formsJ. Pharm. Biomed. Anal.53(3)483-489(2010) 2.Kumaraswamy, K., Gandham, H.B., Prasad, R.J.D., et al.Isolation and characterization of novel degradation products of valsartan by NMR and high resolution mass spectroscopy: Development and validation of valsartan by UPLCAsian J. Chem.32(5)1064-1068(2020)
















