DB818 didrochloride is the didrochloride salt form of DB818 . DB818 didrochloride is an inhibitor for Homeobox A9 (HOXA9). DB818 didrochloride reduces the formation of HOXA9-DNA complexes, inhibits the growth and induces apoptosis in AML cell lines OCI/AML3, MV4-11, and THP-1.
References:
[1]. Sonoda Y, et al. Effects of HOXA9 Inhibitor DB818 on the Growth of Acute Myeloid Leukaemia Cells. Anticancer Res. 2021 Apr;41(4):1841-1847.
















