GlpBio

Combretastatin A1 phosphate

目录号: GC68891纯度: >98.00%同义词: Oxi4503; CA1P; Combretastatin A1 diphosphate
Combretastatin A1 phosphate (Oxi4503; CA1P; Combretastatin A1 diphosphate) 是一种有效的血管破坏剂。Combretastatin A1 phosphate 对肿瘤具有抗血管生成作用。Combretastatin A1 phosphate 具有用于胰腺神经内分泌肿瘤研究的潜力。
Combretastatin A1 phosphate
Cas No.: 288847-35-8
规格价格库存数量操作
10mg¥9,945.00现货
1
25mg¥20,880.00现货
1
50mg¥33,300.00现货
1
100mg¥53,280.00现货
1
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文献被引

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产品描述 Description

Combretastatin A1 phosphate (Oxi4503; CA1P; Combretastatin A1 diphosphate) is a potent vascular disruptive agent. Combretastatin A1 phosphate exerts anti-angiogenic effects on tumors. Combretastatin A1 phosphate has the potential for the research of pancreatic neuroendocrine tumors[1][2].

Combretastatin A1 phosphate (100 mg/kg; I.p.; once at day 16 post tumor induction) 显示出抗肿瘤活性，并对小鼠肿瘤发挥抗血管生成作用当与 Demonstrated a significantly decreased mean liver weight compared to livers from non tumor bearing animals, significantly reduced tumor vessels.

[1]. Patterson DM, et al. Phase I clinical and pharmacokinetic evaluation of the vascular-disrupting agent OXi4503 in patients with advanced solid tumors. Clin Cancer Res. 2012 Mar 1;18(5):1415-25.
[2]. Nguyen L, et al. Vascular disruptive agent OXi4503 and anti-angiogenic agent Sunitinib combination treatment prolong survival of mice with CRC liver metastasis. BMC Cancer. 2016 Jul 26;16:533.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
288847-35-8
同义词
Oxi4503; CA1P; Combretastatin A1 diphosphate
分子式
C18H22O12P2
分子量
492.31 g/mol
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol