GLPBio

Coelonin

目录号: GC77329纯度: 不显示同义词: 2,7-二羟基-4-甲氧基-9,10-二氢菲
Coelonin is a dihydrophenanthrene with anti-inflammation activity. Coelonin inhibits LPS-inducedPTENphosphorylation. Coelonin inhibitsNF-κBactivation andp27Kip1degradation by regulating thePI3K/AKTpathway negatively. Coelonin can inhibitIκBαphosphorylation and degradation and increases the expression ofIκBαprotein.
Coelonin
Cas No.: 82344-82-9
规格价格库存数量操作
1mg¥3,150.00现货
1
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文献被引

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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Coelonin is a dihydrophenanthrene with anti-inflammation activity. Coelonin inhibits LPS-inducedPTENphosphorylation. Coelonin inhibitsNF-κBactivation andp27Kip1degradation by regulating thePI3K/AKTpathway negatively. Coelonin can inhibitIκBαphosphorylation and degradation and increases the expression ofIκBαprotein.

References:
[1].Jiang F, et al. Coelonin, an Anti-Inflammation Active Component of Bletilla striata and Its Potential Mechanism. Int J Mol Sci. 2019 Sep 8;20(18):4422.
[2].Cheng W, et al. Inhibition of inflammation-induced injury and cell migration by coelonin and militarine in PM2.5-exposed human lung alveolar epithelial A549 cells. Eur J Pharmacol. 2021 Apr 5;896:173931.

产品文档 Product Documents

Purity:不显示

化学性质Chemical Properties

CAS 号
82344-82-9
同义词
2,7-二羟基-4-甲氧基-9,10-二氢菲
SMILES
OC(C=C1CC2)=CC(OC)=C1C3=C2C=C(O)C=C3
分子式
C15H14O3
分子量
242.27 g/mol
保存条件
-20°C, sealed storage, away from moisture and light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol