CJC-1295 (acetate)

目录号: GC92120纯度: >98.00%同义词: Modified GRF (1-29); CJC-1295-no DAC; GHRH (1-29)-NH<sub>2</sub>
CJC-1295 (acetate)是生长激素释放激素(GHRH)的合成肽衍生物。

CJC-1295 (acetate)
Cas No.: 863288-34-0
规格价格库存数量操作
5 mg¥448.00现货
1
25 mg¥1,624.00现货
1
50 mg¥2,996.00现货
1
100 mg¥5,544.00现货
1

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

CJC-1295 is a synthetic peptide derivative of growth hormone-releasing hormone (GHRH).1 Unlike CJC-1295-DAC, CJC-1295 does not contain a drug affinity complex (DAC) moiety and has a shorter half-life than the DAC-conjugated version in the blood.2 CJC-1295 increases the secretion of growth hormone in primary rat anterior pituitary cells when used from picomolar to micromolar concentrations and into rat blood when administered subcutaneously at a dose of 1 ?mol/kg.1

References:
[1]. Bridon, D.P., Boudjellab, N., Leger, R., et al.Long lasting growth hormone releasing factor derivatives(2002).
[2]. Teichman, S.L., Neale, A., Lawrence, B., et al.Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adultsJ. Clin. Endocrinol. Metab.91(3)799-805(2006).

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
863288-34-0
同义词
Modified GRF (1-29); CJC-1295-no DAC; GHRH (1-29)-NH<sub>2</sub>
化学名
L-tyrosyl-D-alanyl-L-α-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-glutaminyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-L-leucyl-L-seryl-L-argininamide, acetate
SMILES
NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC([C@]([H])([C@H](CC)C)NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@@H](NC([C@@H](NC([C@H](C)NC([C@@H](NC([C@H](CC(C)C)NC([C@@H](NC([C@H](C)NC([C@H](CC(C)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]([H])(NC([C@H](CC1=CC=CC=C1)NC([C@]([H])([C@H](CC)C)NC([C@H](C)NC([C@@H](NC([C@@H](C)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)CC(O)=O)=O)=O)=O)=O)[C@@H](C)O)=O)CCC(N)=O)=O)CO)=O)CC3=CC=C(C=C3)O)=O)CCCNC(N)=N)=O)CCCCN)=O)C(C)C)=O)=O)=O)CCC(N)=O)=O)=O)CO)=O)=O)CCCNC(N)=N)=O)CCCCN)=O)=O)=O)CCC(N)=O)=O)CC(O)=O)=O)=O)=O)CO)=O)CCCNC(N)=N)=O.CC(O)=O
分子式
C152H252N44O42 • XC2H4O2
分子量
3367.9 g/mol
溶解性
DMF: Slightly soluble,DMSO: 1 mg/ml,Ethanol: Slightly soluble
保存条件
-20&#176;C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol