CIN-16645 is an ionizable amino lipid.1 It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) to deliver single-guide RNA (sgRNA) targeting MHC class II transactivator (CIITA) in T cells.
1.Sridhar, S., Zhang, Y., Harrington, W.F., et al.Compositions and methods for reducing MHC class II in a cell(2022)
















