Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Holt GS, et al. Shigatoxin encoding Bacteriophage ϕ24B modulates bacterial metabolism to raise antimicrobial tolerance. Sci Rep. 2017 Jan 20;7:40424.
[3]. Wood A, et al. The action of three antiseptics/disinfectants against enveloped and non-enveloped viruses. J Hosp Infect. 1998 Apr;38(4):283-95.