CH1055 trietlamine is a NIR-II fluorophore based on a synthetic 970-Da organic molecule. CH1055 trietlamine is a rapidly excreted dye (∼90% excreted through the kidneys within 24 h). CH1055 trietlamine also allows targeted molecular imaging of tumors in vivo when conjugated with anti-EGFR Affibody.
References:
[1]. Antaris AL, et al. A small-molecule dye for NIR-II imaging. Nat Mater. 2016 Feb;15(2):235-42.
[2]. Antaris AL, et al. A small-molecule dye for NIR-II imaging. Nat Mater. 2016;15(2):235-242.