CD39 Protein, Human (sf9, His)

目录号: GC27206纯度: 不显示

CD39蛋白是神经系统中的重要调节因子，通过水解ATP和其他核苷酸来协调嘌呤能神经传递。其酶活性可将血小板活化的ADP水解成AMP，从而有效阻止血小板聚集。

规格	价格	库存	数量	操作
5ug	¥855.00	现货	1
10ug	¥1,332.00	现货	1

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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例

Nature
641, 529–536 (2025)
Nature
628, 630–638 (2024)
Nature
632, 686–694 (2024)
Nature
618, 1017–1023 (2023)
Nature
610, 366–372 (2022)
Cell
187(9):2288-2304 (2024)
Cell
183(7):1867-1883 (2020)
Science
388(6745) (2025)
Science
387(6739) (2025)
Science
387(6734) (2025)
Cell Research
35, 97–116 (2025)
Cell Research
34, 683–706 (2024)
Cell Research
33, 273–287 (2023)
Cell Research
33, 546–561 (2023)
Cell Research
33, 904–922 (2023)
Cell Research
31, 1291–1307 (2021)

产品描述 Description

CD39蛋白是神经系统中的重要调节因子，通过水解ATP和其他核苷酸来协调嘌呤能神经传递。其酶活性可将血小板活化的ADP水解成AMP，从而有效阻止血小板聚集。CD39 蛋白, Human (sf9, His) 是重组的 CD39 蛋白，由 Sf9 insect cells 表达，带有 C-His 标签。

在神经系统中，CD39 蛋白通过水解 ATP 和其他核苷酸，充当嘌呤能神经传递的关键调节剂。其酶活性延伸至预防血小板聚集，因为它能有效地将血小板活化的 ADP 水解为 AMP。值得注意的是，CD39 在水解 ATP 和 ADP 方面表现出同等的能力，强调了其在调节嘌呤能信号通路以及促进神经传递和血小板功能的复杂调节方面的多功能作用。

产品文档 Product Documents

Purity:不显示

Product Data

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Source

Sf9 insect cells

Physical Appearance

Solution.

Shipping Condition

Shipping with dry ice.

Synonyms

CD39 蛋白; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-apyrase; CD39; Entpd1

Apparent Molecular Weight

Approximately 56.7 kDa Da

Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Biological Activity

1. Measured by its ability to hydrolyze the 5’-phosphate groups from the substrate adenosine-5’-triphosphate (ATP) and the specific activity is >5000 pmol/min/µg. 2. Loaded Perenostobart on AHC2 biosensor, can bind CD39 Protein, Human (sf9, His) with an affinity constant of 3.546E-09 M as determined in BLI assay. Loaded Perenostobart on AHC2 biosensor, can bind CD39 Protein, Human (sf9, His) with an affinity constant of 3.546E-09 M as determined in BLI assay.

Formulation

Supplied as a 0.22 μm filtered solution of 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.1. Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.