GlpBio

C9-200

目录号: GC92077纯度: >95.00%
C9-200是一种可电离的阳离子脂质，已被用于形成脂质纳米颗粒（LNPs）。
C9-200
规格价格库存数量操作
1 mg¥406.00现货
1
5 mg¥1,428.00现货
1
10 mg¥2,436.00现货
1
25 mg¥4,564.00现货
1
电话: 400-920-5774Email: sales@glpbio.cn

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

C9-200 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs).1 LNPs containing C9-200 and encapsulating mRNA encoding erythropoietin (EPO) increase serum EPO levels in mice. LNPs containing C9-200 and encapsulating mRNA encoding the Cas9 nuclease and small-guide RNA (sgRNA) targeting transthyretin (TTR) induce 3-fold higher hepatic insertion and deletion (indel) formation than LNPs containing C12-200 and encapsulating mRNA encoding Cas9 in mice.

References:
[1]. Mrksich, K., Padilla, M.S., Joseph, R.A., et al.Influence of ionizable lipid tail length on lipid nanoparticle delivery of mRNA of varying lengthJ. Biomed. Mater. Res. A112(9)1494-1505(2024).

产品文档 Product Documents

Purity:>95.00%Appearance:A solution in ethanol

化学性质Chemical Properties

化学名
1,1'-((2-(4-(2-((2-(bis(2-hydroxynonyl)amino)ethyl)(2-hydroxynonyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(nonan-2-ol)
SMILES
OC(CCCCCCC)CN(CCN(CC(CCCCCCC)O)CC(CCCCCCC)O)CCN1CCN(CCN(CC(CCCCCCC)O)CC(CCCCCCC)O)CC1
分子式
C55H115N5O5
分子量
926.5 g/mol
溶解性
Ethanol: Sparingly soluble: 1-10 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol