GlpBio

Butaprost (free acid)

目录号: GC42995纯度: >95.00%同义词: (±)15deoxy16Shydroxy17cyclobutyl PGE1, 15deoxy16Shydroxy17cyclobutyl PGE1
An EP2-selective prostaglandin E2 analog
Butaprost (free acid)
Cas No.: 433219-55-7
规格价格库存数量操作
1mg¥3,188.00现货
1
5mg¥13,429.00现货
1
10mg¥22,238.00现货
1
500μg¥1,679.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Butaprost is an EP2 selective agonist which has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Prostaglandin free acids generally bind to their cognate receptors with 10 to 100 times the affinity of the corresponding ester derivative. Consistent with this trend, butaprost binds to membranes from EP2 receptor-transfected CHO cells with a Ki value of 2,400 nM, whereas butaprost (free acid) and CAY10399 (the 2-series congener of butaprost free acid) exhibit significantly lower Ki values of 73 and 92 nM, respectively. Butaprost (free acid) is therefore another useful tool for characterizing EP receptor-mediated signalling events.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
433219-55-7
同义词
(±)15deoxy16Shydroxy17cyclobutyl PGE1, 15deoxy16Shydroxy17cyclobutyl PGE1
SMILES
CCCC1(CCC1)[C@@H](O)C/C=C/[C@H]([C@H]2CCCCCCC(O)=O)[C@H](O)CC2=O
分子式
C23H38O5
分子量
394.6 g/mol
溶解性
DMF: 25 mg/ml,DMSO: 25/mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 100 µ g/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol