BPU arrests cell cycle progression in the sub-G1 phase. BPU is an anticancer agent through inhibiting blood vessel formation in tumor tissues.
References:
[1]. Yasser Hussein Issa Mohammed, et al. Discovery of 1-(5-bromopyrazin-2-yl)-1-[3-(trifluorometl)benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies. Sci Rep. 2023, 13, 1.
[2]. Yasser Hussein Issa Mohammed, et al. Discovery of 1-(5-bromopyrazin-2-yl)-1-[3-(trifluorometl)benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies. Scientific Reports. Dec 12.