Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes drolysis and releases the fluorescent product 7-amino-4-metlcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal.
References:
[1]. Tervonen TA, et, al. Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. Oncogene. 2016 Apr 7;35(14):1832-46.